Inner mitochondrial membrane - Revision history

Vipul at 17:35, 20 November 2022

2022-11-20T17:35:23Z

← Older revision		Revision as of 17:35, 20 November 2022
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	==Definition==		==Definition==

	The '''inner mitochondrial membrane''' ('''IMM''') is the ''inner'' membrane of the [[mitochondrion]], an [[organelle]] found in most [[eukaryotic cell]]s. It is an example of a [[biological membrane]]. It comprises a [[lipid bilayer]]. It is highly folded in order to increase its area, with the folds called [[cristae]]. It controls the entry and exit of materials between the [[intermembrane space]] on its outside, and the [[mitochondrial matrix]] on the inside.		The '''inner mitochondrial membrane''' ('''IMM''') is the ''inner'' membrane of the [[mitochondrion]], an [[organelle]] found in most [[eukaryotic cell]]s. It is an example of a [[biological membrane]]. It comprises a [[lipid bilayer]]. It is highly folded in order to increase its area, with the folds called [[cristae]]. It controls the entry and exit of materials between the [[intermembrane space of mitochondrion]] on its outside, and the [[mitochondrial matrix]] on the inside.

	The movement of materials as well as the voltage maintained across the inner mitochondrial membrane are critical to the mitochondrion's role in energy production.		The movement of materials as well as the voltage maintained across the inner mitochondrial membrane are critical to the mitochondrion's role in energy production.
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	\| Location within the mitochondrion \|\| It is close to but not at the boundary of the mitochondrion.		\| Location within the mitochondrion \|\| It is close to but not at the boundary of the mitochondrion.
	\|-		\|-
	\| What's on both sides of it \|\| It fully encloses the [[mitochondrial matrix]]. Outside it is the [[intermembrane space]], and further out is the [[outer mitochondrial membrane]].		\| What's on both sides of it \|\| It fully encloses the [[mitochondrial matrix]]. Outside it is the [[intermembrane space of mitochondrion]], and further out is the [[outer mitochondrial membrane]].
	\|-		\|-
	\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation. The electrochemical potential difference maintained across the membrane is about 180 mV.		\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation. The electrochemical potential difference maintained across the membrane is about 180 mV.

Vipul at 16:22, 20 November 2022

2022-11-20T16:22:00Z

← Older revision		Revision as of 16:22, 20 November 2022
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			{{component of organelle\|mitochondrion}}

	==Definition==		==Definition==

Vipul: /* Summary */

2022-04-02T06:21:46Z

Summary

← Older revision		Revision as of 06:21, 2 April 2022
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	\| Evolutionary origin \|\| According to the [[endosymbiotic theory of mitochondrial origin]], the mitochondrion descends from endosymbiotic prokaryotes inside the eukaryotic cell. The inner mitochondrial membrane, correspondingly descends from the cell membrane of the endosymbiont.		\| Evolutionary origin \|\| According to the [[endosymbiotic theory of mitochondrial origin]], the mitochondrion descends from endosymbiotic prokaryotes inside the eukaryotic cell. The inner mitochondrial membrane, correspondingly descends from the cell membrane of the endosymbiont.
	\|-		\|-
	\| Control of the entry and exit of materials \|\| The inner mitochondrial membrane allows free passage for only: oxygen, carbon dioxide, and water. It is much more selective about allowing ions and small molecules. This is necessary for it to allow for the buildup of an electrochemical gradient (if it were too permeable, diffusion through it would drain any gradient). This is needed for its role in energy storage.		\| Control of the entry and exit of materials \|\| The inner mitochondrial membrane allows free passage for only: oxygen, carbon dioxide, and water. It is much more selective about allowing ions and small molecules, with carriers needed to facilitate the movement of such molecules. This is necessary for it to allow for the buildup of an electrochemical gradient (if it were too permeable, diffusion through it would drain any gradient). This is needed for its role in energy storage.
	\|-		\|-
	\| Function \|\| It helps with energy storage and transfer to ATP by maintaining an electrochemical gradient and controlling the entry and exit of materials to increase or decrease the gradient.		\| Function \|\| It helps with energy storage and transfer to ATP by maintaining an electrochemical gradient and controlling the entry and exit of materials to increase or decrease the gradient.
	\|}		\|}

Vipul: /* Summary */

2022-04-02T06:20:57Z

Summary

← Older revision		Revision as of 06:20, 2 April 2022
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	\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation. The electrochemical potential difference maintained across the membrane is about 180 mV.		\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation. The electrochemical potential difference maintained across the membrane is about 180 mV.
	\|-		\|-
	\| Structural components \|\| Similar to any [[biological membrane]], it has a [[lipid bilayer]] (comprising ~~phosholipids~~) as well as [[integral membrane protein]]s.		\| Structural components \|\| Similar to any [[biological membrane]], it has a [[lipid bilayer]] (comprising phospholipids) as well as [[integral membrane protein]]s.
	\|-		\|-
	\| Chemical constituents \|\| Integral membrane proteins and phospholipids, in a 80:20 ratio (unlike 50:50 for the outer mitochondrial membrane). The chemical composition is similar to that of the cell membrane of bacteria, consistent with the [[endosymbiotic theory of mitochondrial origin]].		\| Chemical constituents \|\| Integral membrane proteins and phospholipids, in a 80:20 ratio (unlike 50:50 for the outer mitochondrial membrane). The chemical composition is similar to that of the cell membrane of bacteria, consistent with the [[endosymbiotic theory of mitochondrial origin]].

Vipul: /* Summary */

2022-01-18T04:38:56Z

Summary

← Older revision		Revision as of 04:38, 18 January 2022
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	\| Type of cells within the organisms that contain the inner mitochondrial membrane \|\| Same as the cells that contain mitochondria: all cells except [[red blood cell]]s in [[mammal]]s (other vertebrates ''do'' have mitochondria in their red blood cells).		\| Type of cells within the organisms that contain the inner mitochondrial membrane \|\| Same as the cells that contain mitochondria: all cells except [[red blood cell]]s in [[mammal]]s (other vertebrates ''do'' have mitochondria in their red blood cells).
	\|-		\|-
	\| Number of inner ~~mitochrondrial~~ membranes per cell \|\| Same as the number of mitochondria: 1 to 1000s, depending on the energy needs of the cell		\| Number of inner mitochondrial membranes per cell \|\| Same as the number of mitochondria: 1 to 1000s, depending on the energy needs of the cell
	\|-		\|-
	\| Size \|\| <math>~70</math> angstrom thickness (very approximate), similar to the outer mitochondrial membrane, compared with mitochondrial diameter of <math>0.5 - 1.0 \mu m</math>, so the thickness is about 1% of the diameter of the mitochondrion. The area is about five times that of the outer mitochondrial membrane, due to the folds called [[cristae]]. High surface area is helpful for its goal of facilitating more energy generation through the transfer of materials (mostly protons) via the membrane.		\| Size \|\| <math>~70</math> angstrom thickness (very approximate), similar to the outer mitochondrial membrane, compared with mitochondrial diameter of <math>0.5 - 1.0 \mu m</math>, so the thickness is about 1% of the diameter of the mitochondrion. The area is about five times that of the outer mitochondrial membrane, due to the folds called [[cristae]]. High surface area is helpful for its goal of facilitating more energy generation through the transfer of materials (mostly protons) via the membrane.

Vipul: /* Summary */

2022-01-17T05:28:45Z

Summary

← Older revision		Revision as of 05:28, 17 January 2022
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	\|-		\|-
	\| Control of the entry and exit of materials \|\| The inner mitochondrial membrane allows free passage for only: oxygen, carbon dioxide, and water. It is much more selective about allowing ions and small molecules. This is necessary for it to allow for the buildup of an electrochemical gradient (if it were too permeable, diffusion through it would drain any gradient). This is needed for its role in energy storage.		\| Control of the entry and exit of materials \|\| The inner mitochondrial membrane allows free passage for only: oxygen, carbon dioxide, and water. It is much more selective about allowing ions and small molecules. This is necessary for it to allow for the buildup of an electrochemical gradient (if it were too permeable, diffusion through it would drain any gradient). This is needed for its role in energy storage.
			\|-
			\| Function \|\| It helps with energy storage and transfer to ATP by maintaining an electrochemical gradient and controlling the entry and exit of materials to increase or decrease the gradient.
	\|}		\|}

Vipul: /* Summary */

2022-01-17T05:24:29Z

Summary

← Older revision		Revision as of 05:24, 17 January 2022
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	\| What's on both sides of it \|\| It fully encloses the [[mitochondrial matrix]]. Outside it is the [[intermembrane space]], and further out is the [[outer mitochondrial membrane]].		\| What's on both sides of it \|\| It fully encloses the [[mitochondrial matrix]]. Outside it is the [[intermembrane space]], and further out is the [[outer mitochondrial membrane]].
	\|-		\|-
	\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation.		\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation. The electrochemical potential difference maintained across the membrane is about 180 mV.
	\|-		\|-
	\| Structural components \|\| Similar to any [[biological membrane]], it has a [[lipid bilayer]] (comprising phosholipids) as well as [[integral membrane protein]]s.		\| Structural components \|\| Similar to any [[biological membrane]], it has a [[lipid bilayer]] (comprising phosholipids) as well as [[integral membrane protein]]s.

Vipul: /* Summary */

2022-01-17T05:07:34Z

Summary

← Older revision		Revision as of 05:07, 17 January 2022
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	\| Number of inner mitochrondrial membranes per cell \|\| Same as the number of mitochondria: 1 to 1000s, depending on the energy needs of the cell		\| Number of inner mitochrondrial membranes per cell \|\| Same as the number of mitochondria: 1 to 1000s, depending on the energy needs of the cell
	\|-		\|-
	\| Size \|\| <math>~70</math> angstrom thickness (very ~~approoximate~~), similar to the outer mitochondrial membrane, compared with mitochondrial diameter of <math>0.5 - 1.0 \mu m</math>, so the thickness is about 1% of the diameter of the mitochondrion. The area is about five times that of the outer mitochondrial membrane, due to the folds called [[cristae]]. High surface area is helpful for its goal of facilitating more energy generation through the transfer of materials (mostly protons) via the membrane.		\| Size \|\| <math>~70</math> angstrom thickness (very approximate), similar to the outer mitochondrial membrane, compared with mitochondrial diameter of <math>0.5 - 1.0 \mu m</math>, so the thickness is about 1% of the diameter of the mitochondrion. The area is about five times that of the outer mitochondrial membrane, due to the folds called [[cristae]]. High surface area is helpful for its goal of facilitating more energy generation through the transfer of materials (mostly protons) via the membrane.
	\|-		\|-
	\| Location within the mitochondrion \|\| It is close to but not at the boundary of the mitochondrion.		\| Location within the mitochondrion \|\| It is close to but not at the boundary of the mitochondrion.

Vipul: /* Summary */

2022-01-17T05:07:21Z

Summary

← Older revision		Revision as of 05:07, 17 January 2022
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	\|-		\|-
	\| Evolutionary origin \|\| According to the [[endosymbiotic theory of mitochondrial origin]], the mitochondrion descends from endosymbiotic prokaryotes inside the eukaryotic cell. The inner mitochondrial membrane, correspondingly descends from the cell membrane of the endosymbiont.		\| Evolutionary origin \|\| According to the [[endosymbiotic theory of mitochondrial origin]], the mitochondrion descends from endosymbiotic prokaryotes inside the eukaryotic cell. The inner mitochondrial membrane, correspondingly descends from the cell membrane of the endosymbiont.
			\|-
			\| Control of the entry and exit of materials \|\| The inner mitochondrial membrane allows free passage for only: oxygen, carbon dioxide, and water. It is much more selective about allowing ions and small molecules. This is necessary for it to allow for the buildup of an electrochemical gradient (if it were too permeable, diffusion through it would drain any gradient). This is needed for its role in energy storage.
	\|}		\|}

Vipul: /* Summary */

2022-01-17T05:03:52Z

Summary

← Older revision		Revision as of 05:03, 17 January 2022
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	\| Size \|\| <math>~70</math> angstrom thickness (very approoximate), similar to the outer mitochondrial membrane, compared with mitochondrial diameter of <math>0.5 - 1.0 \mu m</math>, so the thickness is about 1% of the diameter of the mitochondrion. The area is about five times that of the outer mitochondrial membrane, due to the folds called [[cristae]]. High surface area is helpful for its goal of facilitating more energy generation through the transfer of materials (mostly protons) via the membrane.		\| Size \|\| <math>~70</math> angstrom thickness (very approoximate), similar to the outer mitochondrial membrane, compared with mitochondrial diameter of <math>0.5 - 1.0 \mu m</math>, so the thickness is about 1% of the diameter of the mitochondrion. The area is about five times that of the outer mitochondrial membrane, due to the folds called [[cristae]]. High surface area is helpful for its goal of facilitating more energy generation through the transfer of materials (mostly protons) via the membrane.
	\|-		\|-
	\| Location within the mitochondrion \|\| It is close to but not at the boundary of the mitochondrion. It fully encloses the [[mitochondrial matrix]]. Outside it is the [[intermembrane space]], and further out is the [[outer mitochondrial membrane]].		\| Location within the mitochondrion \|\| It is close to but not at the boundary of the mitochondrion.
			\|-
			\| What's on both sides of it \|\| It fully encloses the [[mitochondrial matrix]]. Outside it is the [[intermembrane space]], and further out is the [[outer mitochondrial membrane]].
	\|-		\|-
	\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation.		\| Electrochemical gradient across the membrane \|\| The outside (the intermembrane space) is more positively charged than the inside (the mitochondrial matrix), and has an excess of protons. Moving protons from inside to outside, against the gradient, requires and absorbs energy. Moving protons back inside releases energy that can be captured through either ATP production or heat generation.